Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | FADS1 | O60427 | 2/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30726102 | 1.00 | CYP1A2 (0.74) | CYP1A2HPGDCYP2C19RAB9ANPC1 | |
| SCHEMBL28945955 | 0.89 | CYP1A2 (0.68) | CYP1A2HPGDCYP2C19RAB9ANPC1 | |
| SCHEMBL31680566 | 0.87 | CYP1A2 (0.89) | CYP1A2HPGDCYP2C19RAB9ANPC1 | |
| SCHEMBL11743614 | 0.87 | NPC1 (0.72) | CYP1A2HPGDCYP2C19RAB9ANPC1 | |
| SCHEMBL733334 | 0.86 | CYP1A2 (0.74) | CYP1A2HPGDCYP2C19RAB9ANPC1 | |
| SCHEMBL392793 | 0.85 | NPC1 (0.70) | RAB9ANPC1KDM4EALDH1A1FADS1 | |
| SCHEMBL733479 | 0.84 | ALDH1A1 (0.69) | CYP1A2HPGDCYP2C19RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL11743643 | 0.84 | NPC1 (0.68) | RAB9ANPC1KDM4EALDH1A1FADS1 | |
| SCHEMBL732543 | 0.83 | CYP1A2 (0.59) | CYP1A2HPGDCYP2C19RAB9ANPC1 | |
| SCHEMBL28154577 | 0.82 | RAB9A (0.67) | CYP1A2HPGDCYP2C19RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510415-A | Synthesis method of quinazolinone compound | 中国人民解放军军事科学院防化研究院 | 2024-02-06 | — | — | CN | disclosed |
| CN-108822046-B | Method for synthesizing quinazolinone compound by one-pot method | 河南大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-104744379-A | Quinazolinone compound and synthetic method thereof | UNIV CHINA THREE GORGES CTGU | 2015-07-01 | — | — | CN | disclosed |