SCHEMBL28015380

SCHEMBL28015380

CC(C)(C)c1cccc(-c2c3ccccc3c(Br)c3ccccc23)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.46
RXRA P19793 2/20 0.41
RXRB P28702 2/20 0.41
ABCG2 Q9UNQ0 1/20 0.39
HDAC8 Q9BY41 2/20 0.36
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
PTPN5 P54829 1/20 0.34
PTAFR P25105 1/20 0.34
ACHE P22303 3/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
SERPINE1 P05121 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2700290 0.83 KIF11 (0.42) KIF11RXRARXRBABCG2ACHE
SCHEMBL28015346 0.81 KIF11 (0.47) KIF11RXRARXRBABCG2HDAC8
SCHEMBL2448770 0.80 TNKS (0.40) KIF11NPC1RAB9AHDAC6
SCHEMBL12415326 0.80 KIF11 (0.39) KIF11RXRARXRBABCG2ACHE
SCHEMBL28458396 0.78 KIF11 (0.39) KIF11RXRARXRBALDH1A1
SCHEMBL600986 0.78 ABCG2 (0.53) KIF11RXRARXRBABCG2TMEM97
SCHEMBL29488281 0.78 ABCG2 (0.53) KIF11RXRARXRBABCG2TMEM97
SCHEMBL12560721 0.77 MAPT (0.44) ACHEALDH1A1L3MBTL1
SCHEMBL2700890 0.77 KIF11 (0.38) KIF11PGRRORARORCRORB
SCHEMBL9612423 0.77 MAPK1 (0.43) CNR1CNR2ACHENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744349-B Electron transport material and use its organic electroluminescent element 捷恩智株式会社 2017-09-22 CN disclosed
CN-103189355-B Electron transport material and organic electroluminescent device using the same JNC CORP. (JP) 2015-08-26 CN disclosed
CN-104744349-A Electron transport material and organic electroluminescence element using same JNC CORP 2015-07-01 CN disclosed