Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | QDPR | P09417 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15603741 | 0.82 | PDK2 (0.43) | PDK2ROCK2MAP4K4GSK3BCLK4 | |
| SCHEMBL8405373 | 0.81 | CYP3A4 (0.44) | PDK2QDPRROCK2MAP4K4GSK3B | |
| SCHEMBL5387522 | 0.80 | PDK2 (0.47) | PDK2 | |
| SCHEMBL12937067 | 0.79 | PDK2 (0.54) | PDK2QDPRROCK2MAP4K4GSK3B | |
| SCHEMBL12937079 | 0.79 | PDK2 (0.54) | PDK2QDPRROCK2MAP4K4GSK3B | |
| SCHEMBL2129264 | 0.78 | PDK2 (0.44) | PDK2 | |
| SCHEMBL13858046 | 0.78 | PDK2 (0.47) | PDK2ROCK2MAP4K4GSK3BCLK4 | |
| SCHEMBL27973277 | 0.77 | KIF11 (0.40) | PDK2GSK3BKIF11 | |
| SCHEMBL28055711 | 0.77 | PDK2 (0.51) | PDK2MAPTLMNASMN1; SMN2 | |
| SCHEMBL14508375 | 0.76 | PDK2 (0.37) | PDK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104628628-B | A kind of fluorenes pyridine nano nickel particles and preparation method thereof | 宁波大学 | 2019-07-02 | — | — | CN | claimed |
| CN-104628628-A | Fluorene pyridine nickle nano-particles and preparation method thereof | UNIV NINGBO | 2015-05-20 | — | — | CN | claimed |
| CN-104628628-A | Fluorene pyridine nickle nano-particles and preparation method thereof | UNIV NINGBO | 2015-05-20 | — | — | CN | disclosed |