SCHEMBL5387522

SCHEMBL5387522

CCC1(CC)c2cc(-c3ccc(-c4ccc(O)cc4)cc3)ccc2-c2ccc(-c3ccc(-c4ccc(O)cc4)cc3)cc21

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 1/20 0.47
▸ ESR1 P03372 7/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ ESR2 Q92731 5/20 0.41
▸ HSD17B1 P14061 4/20 0.41
▸ ALOX5 P09917 1/20 0.41
▸ HSD17B2 P37059 1/20 0.39
▸ TDP2 O95551 1/20 0.39
▸ ABL1 P00519 2/20 0.39
▸ ABCB1 P08183 2/20 0.39
▸ BCR P11274 2/20 0.39
▸ HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26135919 0.84 MEN1 (0.42) PDK2ESR1MEN1KMT2AESR2
SCHEMBL17197380 0.80 MGLL (0.44) PDK2ESR1HSD17B10
SCHEMBL27964989 0.80 MGLL (0.44) PDK2ESR1HSD17B10
SCHEMBL28015675 0.80 PDK2 (0.48) PDK2
SCHEMBL2129264 0.79 PDK2 (0.44) PDK2
SCHEMBL27973277 0.79 KIF11 (0.40) PDK2MEN1KMT2A
SCHEMBL28055711 0.79 PDK2 (0.51) PDK2MEN1KMT2A
SCHEMBL14627909 0.79 PDK2 (0.51) PDK2ESR1MEN1KMT2AESR2
SCHEMBL16017840 0.79 PDK2 (0.51) PDK2ESR1MEN1KMT2AESR2
SCHEMBL14508375 0.78 PDK2 (0.37) PDK2TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6867243-B2 Light emitting polymer UNIVERSITY OF HULL (GB) 2005-03-15 — — US claimed
US-20030119936-A1 Light emitting polymer HULL, UNIVERSITY OF (GB) 2003-06-26 — — US claimed
US-7265163-B2 Light emitting polymer UNIVERSITY OF HULL (GB) 2007-09-04 — — US disclosed
US-20070194277-A1 LIGHT EMITTING POLYMER O'NEILL MARY 2007-08-23 — — US disclosed
US-7199167-B2 Light emitting polymer UNIVERSITY OF HULL (GB) 2007-04-03 — — US disclosed
US-7166239-B2 Light emitting polymer UNIVERSITY OF HULL (GB) 2007-01-23 — — US disclosed
US-7118787-B2 Liquid crystal alignment layer UNIVERSITY OF HULL (GB) 2006-10-10 — — US disclosed
US-7081307-B2 Light emitter for a display UNIVERSITY OF HULL (GB) 2006-07-25 — — US disclosed
US-20050096404-A1 Light emitting polymer UNIVERSITY OF HULL (GB) 2005-05-05 — — US disclosed
US-6867243-B2 Light emitting polymer UNIVERSITY OF HULL (GB) 2005-03-15 — — US disclosed
US-20050040396-A1 Light emitter for a display UNIVERSITY OF HULL (GB) 2005-02-24 — — US disclosed
US-20050004252-A1 Light emitting polymer UNIVERSITY OF HULL (GB) 2005-01-06 — — US disclosed
US-20050004251-A1 Light emitting polymer UNIVERSITY OF HULL (GB) 2005-01-06 — — US disclosed
US-6830831-B2 For use in backlights, electronic apparatus and security viewers UNIVERSITY OF HULL (GB) 2004-12-14 — — US disclosed
US-20030119936-A1 Light emitting polymer HULL, UNIVERSITY OF (GB) 2003-06-26 — — US disclosed
US-20030099862-A1 Light emitter for a display HULL, UNIVERSITY OF (GB) 2003-05-29 — — US disclosed
US-20030099785-A1 Liquid crystal alignment layer UNIVERSITY OF HULL (GB) 2003-05-29 — — US disclosed
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