Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 11/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15960053 | 1.00 | CHAT (0.47) | CHATALDH1A1PYGLGRIK1GRIK2 | |
| SCHEMBL28015751 | 0.89 | CHAT (0.45) | CHATALDH1A1PYGLGRIK1GRIK2 | |
| SCHEMBL256052 | 0.84 | CHAT (0.50) | CHATALDH1A1PYGLGRIK1GRIK2 | |
| SCHEMBL14833060 | 0.81 | CHAT (0.47) | CHATALDH1A1PYGLGRIK1GRIK2 | |
| SCHEMBL9049523 | 0.81 | PYGL (0.47) | CHATALDH1A1PYGLGRIK1GRIK2 | |
| SCHEMBL5540657 | 0.81 | ALDH1A1 (0.50) | CHATALDH1A1PYGLGRIK1GRIK2 | |
| SCHEMBL5540658 | 0.81 | ALDH1A1 (0.50) | CHATALDH1A1PYGLGRIK1GRIK2 | |
| SCHEMBL14833783 | 0.81 | PYGL (0.47) | CHATALDH1A1PYGLGRIK1GRIK2 | |
| SCHEMBL14833059 | 0.81 | CHAT (0.47) | CHATALDH1A1PYGLGRIK1GRIK2 | |
| SCHEMBL9047326 | 0.81 | ALDH1A1 (0.45) | CHATALDH1A1PYGLGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |