Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.58 |
| ▸ | KMO | O15229 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RPA1 | P27694 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | DDT | P30046 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CDH1 | P12830 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015464 | 0.86 | MAP4K4 (0.48) | MAP4K4KMOEGLN1MAPT | |
| SCHEMBL28241485 | 0.84 | DDT (0.55) | MAP4K4KMOP4HTMDDTL3MBTL1 | |
| SCHEMBL19835341 | 0.81 | SLC6A3 (0.51) | MAP4K4SMN1; SMN2L3MBTL1KDM4ENPC1 | |
| SCHEMBL411891 | 0.79 | MAP4K4 (0.49) | MAP4K4KMOSMN1; SMN2PTGS2EGLN1 | |
| SCHEMBL4725410 | 0.77 | MAP4K4 (0.68) | MAP4K4KMOSMN1; SMN2RPA1PTGS2 | |
| SCHEMBL440826 | 0.76 | PTGDR2 (0.50) | MAP4K4KMOL3MBTL1MAPT | |
| SCHEMBL25201104 | 0.76 | DDT (0.51) | MAP4K4KMORPA1P4HTMDDT | |
| SCHEMBL30680327 | 0.75 | CNR2 (0.66) | MAP4K4KMO | |
| SCHEMBL411450 | 0.75 | CNR2 (0.66) | MAP4K4KMO | |
| SCHEMBL25174367 | 0.75 | KMO (0.72) | MAP4K4KMOSMN1; SMN2RPA1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640844-B | The preparation method of 4-amino-5-fluorine-3-halo-6-(substituted) pyridine-2-formic acid esters | 美国陶氏益农公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-104640844-A | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates-2-formate | DOW AGROSCIENCES LLC | 2015-05-20 | — | — | CN | disclosed |