Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016243 | 0.93 | MAPT (0.56) | F2MAPTKLKB1THRBKLK1 | |
| SCHEMBL2564484 | 0.92 | F2 (0.60) | F2MAPTKLKB1THRBTP53 | |
| SCHEMBL28016276 | 0.92 | F2 (0.56) | F2MAPTKLKB1THRBKLK1 | |
| SCHEMBL2569730 | 0.90 | F2 (0.58) | F2MAPTKLKB1THRBTP53 | |
| SCHEMBL2564190 | 0.89 | MAPT (0.69) | F2MAPTKLKB1THRBTP53 | |
| SCHEMBL2572246 | 0.89 | F2 (0.58) | F2MAPTKLKB1THRBTP53 | |
| SCHEMBL14688288 | 0.89 | MAPT (0.58) | F2MAPTKLKB1THRBTP53 | |
| SCHEMBL2567902 | 0.89 | F2 (0.57) | F2MAPTKLKB1THRBTP53 | |
| SCHEMBL2561284 | 0.89 | GAA (0.61) | F2MAPTKLKB1THRBTP53 | |
| SCHEMBL2564273 | 0.88 | F2 (0.58) | F2MAPTKLKB1THRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102918034-B | Polysubstituted aromatic compounds as inhibitors of thrombin | VERSEON CORP | 2015-06-03 | — | — | CN | claimed |