Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016154 | 0.93 | F2 (0.57) | MAPTTHRBF2GAAKLKB1 | |
| SCHEMBL28016807 | 0.92 | F2 (0.53) | MAPTTHRBF2GAAKLKB1 | |
| SCHEMBL2564484 | 0.91 | F2 (0.60) | MAPTTHRBF2GAAKLKB1 | |
| SCHEMBL2561284 | 0.90 | GAA (0.61) | MAPTTHRBF2GAAKLKB1 | |
| SCHEMBL14687550 | 0.88 | MAPT (0.72) | MAPTTHRBF2GAAKLKB1 | |
| SCHEMBL14688731 | 0.88 | MAPT (0.72) | MAPTTHRBF2GAAKLKB1 | |
| SCHEMBL14688970 | 0.88 | F2 (0.61) | MAPTTHRBF2GAAKLKB1 | |
| SCHEMBL2554308 | 0.88 | GAA (0.61) | MAPTTHRBF2GAAKLKB1 | |
| SCHEMBL2567902 | 0.88 | F2 (0.57) | MAPTTHRBF2GAAKLKB1 | |
| SCHEMBL2564273 | 0.87 | F2 (0.58) | MAPTTHRBF2GAAKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102918034-B | Polysubstituted aromatic compounds as inhibitors of thrombin | VERSEON CORP | 2015-06-03 | — | — | CN | claimed |