Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.44 |
| ▸ | KLK1 | P06870 | 2/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016807 | 0.92 | F2 (0.53) | F2HTTRAB9AMEN1ALDH1A1 | |
| SCHEMBL28016154 | 0.92 | F2 (0.57) | F2ALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL2569658 | 0.91 | F2 (0.60) | F2HTTRAB9AMEN1ALDH1A1 | |
| SCHEMBL2566670 | 0.87 | F2 (0.69) | F2RAB9APOLBKMT2AKLKB1 | |
| SCHEMBL2568116 | 0.87 | F2 (0.57) | F2HTTRAB9AMEN1ALDH1A1 | |
| SCHEMBL2561986 | 0.87 | KLKB1 (0.55) | F2HTTRAB9AMEN1ALDH1A1 | |
| SCHEMBL2569334 | 0.86 | KLKB1 (0.57) | F2KLKB1KLK1MAPTTHRB | |
| SCHEMBL2563383 | 0.85 | F2 (0.72) | F2RAB9AALDH1A1LMNAPOLB | |
| SCHEMBL2555846 | 0.85 | F2 (0.57) | F2RAB9AMEN1CYP1A2POLB | |
| SCHEMBL2568165 | 0.85 | F2 (0.60) | F2HTTMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102918034-B | Polysubstituted aromatic compounds as inhibitors of thrombin | VERSEON CORP | 2015-06-03 | — | — | CN | claimed |