Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CTRL | P40313 | 1/20 | 0.38 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14688431 | 0.84 | F2 (0.60) | F2KLKB1MAPTF10SMN1; SMN2 | |
| SCHEMBL14688245 | 0.84 | F2 (0.54) | F2KLKB1MAPTF10PLG | |
| SCHEMBL14688670 | 0.84 | F2 (0.57) | F2MAPTF10SMN1; SMN2HPGD | |
| SCHEMBL28016276 | 0.83 | F2 (0.56) | F2KLKB1MAPTHPGDKLK1 | |
| SCHEMBL28016807 | 0.82 | F2 (0.53) | F2KLKB1MAPTHPGDKLK1 | |
| SCHEMBL2569658 | 0.82 | F2 (0.60) | F2KLKB1MAPTF10SMN1; SMN2 | |
| SCHEMBL2568614 | 0.81 | F2 (0.54) | F2KLKB1MAPTF10SMN1; SMN2 | |
| SCHEMBL2575262 | 0.81 | F2 (0.56) | F2KLKB1MAPTF10HPGD | |
| SCHEMBL14688377 | 0.81 | F2 (0.59) | F2KLKB1MAPTF10USP2 | |
| SCHEMBL2573449 | 0.78 | F2 (0.64) | F2MAPTSMN1; SMN2HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102918034-B | Polysubstituted aromatic compounds as inhibitors of thrombin | VERSEON CORP | 2015-06-03 | — | — | CN | claimed |