Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.53 |
| ▸ | CFD | P00746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016276 | 0.92 | F2 (0.56) | F2CFDHTTKDM4EMAPT | |
| SCHEMBL28016243 | 0.92 | MAPT (0.56) | F2KDM4EMAPTTHRBKLKB1 | |
| SCHEMBL2569658 | 0.90 | F2 (0.60) | F2HTTKDM4EMAPTTHRB | |
| SCHEMBL14687509 | 0.87 | MAPT (0.59) | F2HTTKDM4EMAPTTHRB | |
| SCHEMBL14688360 | 0.87 | MAPT (0.59) | F2HTTKDM4EMAPTTHRB | |
| SCHEMBL14688774 | 0.87 | F2 (0.61) | F2HTTKDM4EMAPTTHRB | |
| SCHEMBL28016154 | 0.84 | F2 (0.57) | F2KDM4EMAPTTHRBKLKB1 | |
| SCHEMBL2564978 | 0.84 | F2 (0.53) | F2HTTKDM4EMAPTTHRB | |
| SCHEMBL14688467 | 0.84 | POLB (0.55) | F2MAPTKLKB1KLK1TP53 | |
| SCHEMBL2573709 | 0.84 | GRM5 (0.55) | F2HTTKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102918034-B | Polysubstituted aromatic compounds as inhibitors of thrombin | VERSEON CORP | 2015-06-03 | — | — | CN | claimed |