Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | NAAA | Q02083 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332405 | 0.94 | NAAA (0.70) | TSHRHTTHPGDNAAAL3MBTL1 | |
| SCHEMBL11330575 | 0.94 | NAAA (0.70) | TSHRHTTHPGDNAAAL3MBTL1 | |
| SCHEMBL19210845 | 0.88 | TSHR (1.00) | TSHRHTTHPGDNAAAL3MBTL1 | |
| SCHEMBL28692142 | 0.86 | TSHR (0.66) | TSHRHTTHPGDNAAAL3MBTL1 | |
| SCHEMBL26598043 | 0.83 | HPGD (0.71) | TSHRHTTHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL18946096 | 0.83 | TSHR (0.53) | TSHRHTTHPGDNAAASMN1; SMN2 | |
| SCHEMBL4352870 | 0.82 | KMT2A (0.55) | TSHRHTTHPGDNAAAL3MBTL1 | |
| SCHEMBL164069 | 0.81 | TSHR (0.80) | TSHRHTTHPGDNAAAL3MBTL1 | |
| SCHEMBL486382 | 0.81 | TSHR (0.80) | TSHRHTTHPGDNAAAL3MBTL1 | |
| SCHEMBL6273378 | 0.81 | HTT (0.86) | TSHRHTTHPGDNAAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466799-A | Preparation method of N-substituted phthalimide compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-114890856-B | Method for synthesizing 2,2' -biphenyl-1-carboxylic acid derivative | 华南理工大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-116535344-A | Preparation method of phthalimide compound | 华南理工大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-114890856-A | Method for synthesizing 2,2' -biphenyl-1-carboxylic acid derivative | 华南理工大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-111471023-A | Method for synthesizing quinazolinone compound under photocatalysis condition | 河南大学 | 2020-07-31 | — | — | CN | disclosed |
| CN-103224498-B | Two kinds of azoles the novel synthesis of quinazolinone fused heterocycle | CHEN DINGBEN (CN) | 2015-10-28 | — | — | CN | disclosed |