SCHEMBL4352870

SCHEMBL4352870

CCNC(=O)c1ccccc1I

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.51
TSHR P16473 1/20 0.50
HTT P42858 1/20 0.50
BRD4 O60885 2/20 0.48
CA1 P00915 1/20 0.45
CA9 Q16790 1/20 0.45
HCRTR1 O43613 1/20 0.45
CXCR2 P25025 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 2/20 0.44
ADRA1D P25100 1/20 0.43
ADRA1A P35348 1/20 0.43
ADRA1B P35368 1/20 0.43
NAAA Q02083 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31483721 0.86 HTT (0.64) KMT2AL3MBTL1TSHRHTTBRD4
SCHEMBL26417076 0.86 HTT (0.64) KMT2AL3MBTL1TSHRHTTBRD4
SCHEMBL22059502 0.82 TAS1R3 (0.45) KMT2AL3MBTL1TSHRHTTBRD4
SCHEMBL28016258 0.82 TSHR (0.77) L3MBTL1TSHRHTTHCRTR1ALDH1A1
SCHEMBL18309056 0.80 MEN1 (0.50) KMT2AMEN1TDP1TSHRHTT
SCHEMBL8814848 0.80 KMT2A (0.50) KMT2AMEN1TDP1TSHRHTT
SCHEMBL19746790 0.80 POLB (0.57) KMT2AMEN1TDP1TSHRHTT
SCHEMBL22059503 0.80 HPGD (0.49) KMT2AMEN1L3MBTL1ALDH1A1HPGD
SCHEMBL11330575 0.80 NAAA (0.70) L3MBTL1TSHRHTTHCRTR1ALDH1A1
SCHEMBL11332405 0.80 NAAA (0.70) L3MBTL1TSHRHTTHCRTR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466799-B N-substituted phthalic acid diamide preparation method of imine compound 西北师范大学 2024-12-24 CN claimed
CN-117466799-B N-substituted phthalic acid diamide preparation method of imine compound 西北师范大学 2024-12-24 CN disclosed
CN-117466799-A Preparation method of N-substituted phthalimide compound 西北师范大学 2024-01-30 CN disclosed
EP-2065357-B1 Improved process for the catalytic synthesis of diaryl ethers SALTIGO GMBH (DE) 2014-04-23 EP disclosed
US-8304550-B2 Process for the catalytic synthesis of diaryl ethers SALTIGO GMBH (DE) 2012-11-06 US disclosed
US-8115000-B2 Pyrazine derivatives and uses thereof in renal monitoring MALLINCKRODT LLC (US) 2012-02-14 US disclosed
US-20100098633-A1 SELECTIVE SEPRASE INHIBITORS MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2010-04-22 US disclosed
US-20090198053-A1 Pyrazine Derivatives and Uses Thereof in Renal Monitoring MEDIBEACON INC. 2009-08-06 US disclosed
US-20090143594-A1 PROCESS FOR THE CATALYTIC SYNTHESIS OF DIARYL ETHERS SALTIGO GMBH (DE) 2009-06-04 US disclosed
CN-101445437-A Improved process for the catalytic synthesis of diaryl ethers SALTIGO GMBH (DE) 2009-06-03 CN disclosed
US-RE36562-E CARBOXAMIDE-SUBSTITUTED THIOPHENES MONSANTO COMPANY (US) 2000-02-08 US disclosed
US-5998466-A PREPLANTING MONSANTO COMPANY (US) 1999-12-07 US disclosed
US-5849723-A Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 1998-12-15 US disclosed
US-5834447-A THIOPHENE DERIVATIVES MONSANTO COMPANY (US) 1998-11-10 US disclosed
US-5811411-A Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 1998-09-22 US disclosed
US-5705513-A HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS MONSANTO COMPANY (US) 1998-01-06 US disclosed
US-5693667-A Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 1997-12-02 US disclosed
US-5498630-A SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES MONSANTO COMPANY (US) 1996-03-12 US disclosed
WO-1993007751-A1 FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS MONSANTO COMPANY (US) 1993-04-29 WO disclosed
EP-0538231-A1 Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 1993-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100098633-A1 SELECTIVE SEPRASE INHIBITORS SLC6A7, DNPEP, PREP KMT2A 2165/4885MEN1 2705/4885TDP1 3266/4885
US-20090143594-A1 PROCESS FOR THE CATALYTIC SYNTHESIS OF DIARYL ETHERS ARSA, AHR, AOC2 KMT2A 426/4885MEN1 2795/4885TDP1 4474/4885
US-20090198053-A1 Pyrazine Derivatives and Uses Thereof in Renal Monitoring GLS, CYP3A5, PYCR1 KMT2A 3926/4885MEN1 2046/4885TDP1 3113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.