SCHEMBL28016287

SCHEMBL28016287

OC1(Br)CC=CC=C1c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL365627 0.81 ESR1 (0.32) ESR1ESR2
SCHEMBL3728491 0.81 ALDH1A1 (0.31)
Methane SCHEMBL28012238 0.79 ESR1 (0.31) ESR1ESR2
SCHEMBL27709376 0.78 CYP19A1 (0.30)
SCHEMBL27712623 0.78 TRPA1 (0.31) ESR1ESR2
SCHEMBL23203047 0.78 CYP1A2 (0.31) ESR1ESR2
SCHEMBL28463415 0.78
SCHEMBL1863591 0.78
SCHEMBL28933571 0.77
SCHEMBL28372540 0.77 ESR1 (0.31) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104628499-A Method for preparing 2'-bromo -2-hydroxy-biphenyl compound UNIV TAIZHOU 2015-05-20 CN disclosed