SCHEMBL28016339

SCHEMBL28016339

C(=Cc1ccccc1-c1ccccc1)c1ccccc1.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 5/20 0.52
TRPA1 O75762 2/20 0.52
BACE1 P56817 1/20 0.49
PELI1 Q96FA3 1/20 0.47
MAOB P27338 2/20 0.42
PTPN1 P18031 1/20 0.42
PTPN6 P29350 1/20 0.42
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2B Q13224 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
CYP19A1 P11511 1/20 0.41
MAOA P21397 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536597 0.98 NFE2L2 (0.54) NFE2L2TRPA1BACE1PELI1MAOB
SCHEMBL536598 0.98 NFE2L2 (0.54) NFE2L2TRPA1BACE1PELI1MAOB
Bromide SCHEMBL27518372 0.96 NFE2L2 (0.52) NFE2L2TRPA1BACE1PELI1MAOB
SCHEMBL28161230 0.94 NFE2L2 (0.50) NFE2L2TRPA1BACE1PELI1MAOB
Ethylene SCHEMBL28238596 0.92 NFE2L2 (0.48) NFE2L2TRPA1BACE1PELI1MAOB
SCHEMBL15484098 0.91 PELI1 (0.51) NFE2L2TRPA1BACE1PELI1MAOB
SCHEMBL15484097 0.91 PELI1 (0.51) NFE2L2TRPA1BACE1PELI1MAOB
SCHEMBL27671423 0.89 NFE2L2 (0.50) NFE2L2TRPA1BACE1PELI1MAOB
SCHEMBL3963459 0.89 BACE1 (0.51) NFE2L2TRPA1BACE1PELI1MAOB
Biphenyl SCHEMBL15319559 0.89 NFE2L2 (0.54) NFE2L2TRPA1BACE1PELI1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104789381-A Multiple-effect laundry detergent easy to clean QINGDAO DONGCHANG RUI TEXTILE PRODUCT CO LTD 2015-07-22 CN disclosed