SCHEMBL3963459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28161230	0.96	NFE2L2 (0.50)	BACE1CA1MGLLPELI1NFE2L2
	SCHEMBL536598	0.91	NFE2L2 (0.54)	BACE1PELI1NFE2L2TRPA1GRIN2D
	SCHEMBL536597	0.91	NFE2L2 (0.54)	BACE1PELI1NFE2L2TRPA1GRIN2D
	SCHEMBL28016339	0.89	NFE2L2 (0.52)	BACE1PELI1NFE2L2TRPA1GRIN2D
	SCHEMBL15484098	0.89	PELI1 (0.51)	BACE1CA1MGLLPELI1NFE2L2
	Bromide SCHEMBL27518372	0.89	NFE2L2 (0.52)	BACE1PELI1NFE2L2TRPA1GRIN2D
	SCHEMBL15484097	0.89	PELI1 (0.51)	BACE1CA1MGLLPELI1NFE2L2
	SCHEMBL29244372	0.87	ALDH1A1 (0.48)	BACE1NFE2L2TRPA1HDAC2HDAC1
	Biphenyl SCHEMBL15319559	0.87	NFE2L2 (0.54)	BACE1CA1MGLLPELI1NFE2L2
	SCHEMBL284706	0.87	GRIN2D (0.48)	BACE1PELI1NFE2L2TRPA1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.