Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17103554 | 0.77 | HTR2C (0.41) | SMN1; SMN2MAPK1ALDH1A1TSHRHTR1A | |
| SCHEMBL7362512 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2MAPK1ALDH1A1TSHRNPC1 | |
| SCHEMBL6539807 | 0.75 | HTT (0.54) | SMN1; SMN2MAPK1ALDH1A1KDM4ETP53 | |
| SCHEMBL535645 | 0.74 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4ENPSR1 | |
| SCHEMBL522409 | 0.74 | — | — | |
| SCHEMBL6539854 | 0.73 | HTT (0.45) | SMN1; SMN2MAPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL947129 | 0.72 | PTGDR2 (0.38) | SMN1; SMN2MAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL910513 | 0.72 | CYP1A2 (0.43) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9033675 | 0.71 | PTGDR2 (0.40) | SMN1; SMN2MAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL10911290 | 0.71 | DRD1 (0.42) | SMN1; SMN2MAPK1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023322-A | New bicyclic nucleoside and oligomer prepared therefrom | 伯尔尼大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-109562122-A | Oligonucleotides, composition and its method | 波涛生命科学有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109462995-A | The method and composition of bioactivator | 波涛生命科学有限公司 | 2019-03-12 | — | — | CN | disclosed |
| CN-104661664-A | Chiral control | WAVE LIFE SCIENCES PTY LTD | 2015-05-27 | — | — | CN | disclosed |