SCHEMBL17103554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6539807	0.82	HTT (0.54)	MAPK1SMN1; SMN2TLR8ALDH1A1XDH
	SCHEMBL28867049	0.81	HTR2C (0.41)	HTR2CMAPK1SMN1; SMN2TLR8ALDH1A1
	SCHEMBL1667585	0.81	HTR1A (0.56)	MAPK1SMN1; SMN2ALDH1A1GAAHTR1A
	SCHEMBL6539854	0.81	HTT (0.45)	MAPK1SMN1; SMN2TLR8ALDH1A1NFKB1
	SCHEMBL4334443	0.80	ALDH1A1 (0.55)	HTR2CSMN1; SMN2TLR8ALDH1A1GAA
	SCHEMBL535645	0.79	ALDH1A1 (0.50)	ALDH1A1GAA
	SCHEMBL28016352	0.77	SMN1; SMN2 (0.38)	MAPK1SMN1; SMN2ALDH1A1GAAHTR1A
	SCHEMBL9622718	0.77	CYP3A4 (0.43)	HTR2CTLR8ALDH1A1GAAXDH
	Formamide SCHEMBL28158245	0.77	SMN1; SMN2 (0.51)	MAPK1SMN1; SMN2ALDH1A1GAAHTR1A
	SCHEMBL947129	0.76	PTGDR2 (0.38)	MAPK1SMN1; SMN2ALDH1A1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.