Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12184667 | 0.64 | — | — | |
| SCHEMBL18951829 | 0.64 | — | — | |
| SCHEMBL17244085 | 0.63 | — | — | |
| SCHEMBL30103254 | 0.61 | ALOX15 (0.39) | ALOX15USP2CYP3A4HSD11B1 | |
| SCHEMBL21827729 | 0.59 | ALOX15 (0.35) | ALOX15SMN1; SMN2CYP3A4 | |
| SCHEMBL8675008 | 0.59 | ALOX15 (0.40) | ALOX15CYP3A4HSD11B1 | |
| SCHEMBL11781582 | 0.58 | ALOX15 (0.39) | ALOX15HSD11B1 | |
| SCHEMBL8444775 | 0.58 | ALOX15 (0.39) | ALOX15CYP3A4HSD11B1 | |
| SCHEMBL12872912 | 0.57 | ALOX15 (0.41) | ALOX15 | |
| SCHEMBL4160213 | 0.57 | CHRM2 (0.36) | ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788485-A | Process for preparing antiviral agent | BRISTOL MYERS SQUIBB CO | 2015-07-22 | — | — | CN | disclosed |
| CN-102675355-B | Process for preparing the antiviral agent [1S-(1alpha,3 alpha,4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | BRISTOL MYERS SQUIBB CO | 2015-05-06 | — | — | CN | disclosed |