Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11932093 | 1.00 | MAPT (0.41) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL16748974 | 1.00 | MAPT (0.41) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL11932087 | 0.89 | KMT2A (0.40) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL517023 | 0.89 | KMT2A (0.40) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL6899887 | 0.89 | SMN1; SMN2 (0.47) | MEN1KMT2ALMNACYP2C9KDM4E | |
| SCHEMBL10347036 | 0.87 | ABCB11 (0.42) | MAPTNPSR1LMNACYP1A2KDM4E | |
| SCHEMBL9899896 | 0.87 | HDAC4 (0.42) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL1907200 | 0.87 | ABCB11 (0.42) | MAPTNPSR1LMNACYP1A2KDM4E | |
| SCHEMBL9904051 | 0.87 | HDAC4 (0.42) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL11932088 | 0.87 | POLB (0.46) | MAPTNPSR1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492361-B | Substituted 1-benzylcycloalkylcarboxlic acids and use thereof | BAYER IP GMBH | 2015-07-15 | — | — | CN | disclosed |