Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TAF1 | P21675 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26259699 | 0.74 | ALDH1A1 (0.39) | CREBBPKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL1420318 | 0.72 | AHR (0.50) | AHRCREBBPBRD4TAF1BRPF1 | |
| SCHEMBL18000241 | 0.72 | AHR (0.55) | AHRCREBBPBRD4TAF1BRPF1 | |
| SCHEMBL97591 | 0.72 | AHR (0.50) | AHRCREBBPBRD4TAF1BRPF1 | |
| SCHEMBL29361477 | 0.72 | AHR (0.50) | AHRCREBBPBRD4TAF1BRPF1 | |
| SCHEMBL5012545 | 0.71 | GRM5 (0.49) | CREBBPKEAP1CA1CA2KDM4E | |
| Hydrochloric Acid SCHEMBL27757229 | 0.71 | AHR (0.48) | AHRCREBBPBRD4TAF1BRPF1 | |
| Hydrochloric Acid SCHEMBL3826755 | 0.71 | AHR (0.48) | AHRCREBBPBRD4TAF1BRPF1 | |
| Hydrochloric Acid SCHEMBL29363603 | 0.71 | AHR (0.48) | AHRCREBBPBRD4TAF1BRPF1 | |
| SCHEMBL3839029 | 0.70 | KDM4E (0.49) | CREBBPKDM4EMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603127-A | Complement pathway modulators and uses thereof | NOVARTIS AG | 2015-05-06 | — | — | CN | disclosed |