Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819521 | 0.87 | IP6K1 (0.67) | MAOBBCHELMNAKDM4EHSD17B10 | |
| SCHEMBL28819517 | 0.87 | IP6K1 (0.67) | MAOBBCHELMNAKDM4EHSD17B10 | |
| SCHEMBL28017664 | 0.81 | MAPT (0.57) | MAOBBCHELMNAKDM4EHSD17B10 | |
| SCHEMBL28017674 | 0.80 | IP6K1 (0.56) | MAOBHSD17B10CYP1B1IP6K1ABCG2 | |
| SCHEMBL28819820 | 0.80 | IP6K1 (0.56) | MAOBLMNAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28017127 | 0.80 | IP6K1 (0.56) | MAOBLMNAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28017665 | 0.78 | IP6K1 (0.54) | MAOBLMNAHSD17B10ALDH1A1CYP1B1 | |
| SCHEMBL28017668 | 0.78 | IP6K1 (0.54) | MAOBLMNAHSD17B10ALDH1A1CYP1B1 | |
| SCHEMBL28017157 | 0.77 | IP6K1 (0.53) | MAOBLMNAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL31298986 | 0.76 | MAOB (0.86) | MAOBBCHELMNAALDH1A1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803927-A | Chalcone analogue containing 2-methyl-4-oxo-quinazoline-6-base, and preparation method and application thereof | UNIV CAPITAL NORMAL | 2015-07-29 | — | — | CN | disclosed |