Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819517 | 0.87 | IP6K1 (0.67) | IP6K1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28819521 | 0.87 | IP6K1 (0.67) | IP6K1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28819820 | 0.86 | IP6K1 (0.56) | IP6K1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28017127 | 0.86 | IP6K1 (0.56) | IP6K1MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL28017674 | 0.86 | IP6K1 (0.56) | IP6K1HSD17B10POLBNPSR1MAOA | |
| SCHEMBL28017665 | 0.84 | IP6K1 (0.54) | IP6K1MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL28017668 | 0.84 | IP6K1 (0.54) | IP6K1MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL28017154 | 0.77 | MAOB (0.58) | IP6K1MAPTALDH1A1LMNAP4HB | |
| SCHEMBL28017664 | 0.74 | MAPT (0.57) | IP6K1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30864305 | 0.73 | TDP1 (0.67) | IP6K1MAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803927-A | Chalcone analogue containing 2-methyl-4-oxo-quinazoline-6-base, and preparation method and application thereof | UNIV CAPITAL NORMAL | 2015-07-29 | — | — | CN | disclosed |