Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017668 | 1.00 | IP6K1 (0.54) | IP6K1POLBNPSR1HSD17B10MAPT | |
| SCHEMBL28819521 | 0.88 | IP6K1 (0.67) | IP6K1POLBNPSR1HSD17B10MAPT | |
| SCHEMBL28819517 | 0.88 | IP6K1 (0.67) | IP6K1POLBNPSR1HSD17B10MAPT | |
| SCHEMBL28017674 | 0.87 | IP6K1 (0.56) | IP6K1POLBNPSR1HSD17B10CYP1B1 | |
| SCHEMBL28017127 | 0.87 | IP6K1 (0.56) | IP6K1POLBNPSR1HSD17B10MAPT | |
| SCHEMBL28819820 | 0.87 | IP6K1 (0.56) | IP6K1POLBNPSR1HSD17B10MAPT | |
| SCHEMBL28017157 | 0.84 | IP6K1 (0.53) | IP6K1POLBNPSR1HSD17B10MAPT | |
| SCHEMBL28017154 | 0.78 | MAOB (0.58) | IP6K1HSD17B10MAPTNPC1RAB9A | |
| SCHEMBL13590061 | 0.77 | HSD17B10 (0.69) | IP6K1POLBNPSR1HSD17B10MAPT | |
| SCHEMBL28017664 | 0.75 | MAPT (0.57) | IP6K1HSD17B10MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803927-A | Chalcone analogue containing 2-methyl-4-oxo-quinazoline-6-base, and preparation method and application thereof | UNIV CAPITAL NORMAL | 2015-07-29 | — | — | CN | disclosed |