SCHEMBL28017281

SCHEMBL28017281

Br[PH](c1ccccc1)(c1ccccc1)c1ccccc1.[Pd]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
TDP1 Q9NUW8 2/20 0.37
TSHR P16473 5/20 0.32
TRPA1 O75762 2/20 0.32
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
DAO P14920 1/20 0.32
NAPRT Q6XQN6 1/20 0.32
BBOX1 O75936 1/20 0.32
EHMT2 Q96KQ7 1/20 0.32
EHMT1 Q9H9B1 1/20 0.32
GSK3B P49841 2/20 0.31
MAPK1 P28482 2/20 0.31
HIF1A Q16665 1/20 0.31
PTPN1 P18031 1/20 0.31
BACE1 P56817 1/20 0.31
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
CA12 O43570 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304911 0.97 ALDH1A1 (0.39) ALDH1A1TDP1TSHRTRPA1CES2
Bromide SCHEMBL9723310 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL15466997 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL10277371 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL28738751 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL28993879 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL11771096 0.76 ALDH1A1 (0.39) ALDH1A1TDP1TSHRTRPA1BBOX1
SCHEMBL9723314 0.76 ALDH1A1 (0.39) ALDH1A1TDP1TSHRTRPA1BBOX1
SCHEMBL28694359 0.73 ALDH1A1 (0.36) ALDH1A1TDP1MAPK1
SCHEMBL201090 0.72 ALDH1A1 (0.38) ALDH1A1TDP1TSHRBBOX1EHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104628510-B 2,6,6,8 four replacement 6H benzos [cd] pyrene compounds and the organic electroluminescence device containing which 北京鼎材科技有限公司 2017-03-29 CN disclosed
CN-104628510-A 2,6,6,8-tetra-substituted-6H-benzo[cd]pyrene compound and organic electroluminescence device containing same BEIJING ETERNAL MATERIAL TECHNOLOGY CO LTD 2015-05-20 CN disclosed