SCHEMBL28738751

SCHEMBL28738751

Br[PH](c1ccccc1)(c1ccccc1)c1ccccc1.[Cu]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
TDP1 Q9NUW8 3/20 0.37
TSHR P16473 6/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 1/20 0.35
PARP1 P09874 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
HSD17B10 Q99714 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TRPA1 O75762 2/20 0.32
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
DAO P14920 1/20 0.32
NAPRT Q6XQN6 1/20 0.32
BBOX1 O75936 1/20 0.32
EHMT2 Q96KQ7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304911 0.97 ALDH1A1 (0.39) ALDH1A1TDP1TSHRTRPA1CES2
Bromide SCHEMBL9723310 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL15466997 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL28993879 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL10277371 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL28017281 0.93 ALDH1A1 (0.37) ALDH1A1TDP1TSHRTRPA1CES2
SCHEMBL11771096 0.76 ALDH1A1 (0.39) ALDH1A1TDP1TSHRCYP3A4MAPT
SCHEMBL9723314 0.76 ALDH1A1 (0.39) ALDH1A1TDP1TSHRCYP3A4MAPT
SCHEMBL28694359 0.73 ALDH1A1 (0.36) ALDH1A1TDP1MAPK1
SCHEMBL17881683 0.71 TSHR (0.35) ALDH1A1TDP1TSHRTRPA1BBOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146172-A Preparation method of 7-fluoro-6-amino-2H-1, 4-benzoxazine-3 (4H) -one 帕潘纳(北京)科技有限公司 2024-06-07 CN claimed
CN-118146172-A Preparation method of 7-fluoro-6-amino-2H-1, 4-benzoxazine-3 (4H) -one 帕潘纳(北京)科技有限公司 2024-06-07 CN disclosed
CN-111448280-B Photosensitizing agent and active energy ray-curable composition 积水化学工业株式会社 2023-10-27 CN disclosed
CN-113603662-B Method for preparing 4- (1-ketone-2-propargyl phenyl propane) phthalic anhydride 陕西泰合利华工业有限公司 2023-06-06 CN disclosed
CN-109072066-B Light control material, light control film, and light control laminate 积水化学工业株式会社 2022-05-24 CN disclosed