Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410654 | 0.81 | ALDH1A1 (0.57) | TXNRD1TXNRD3TXNRD2ERN1TSHR | |
| SCHEMBL30929373 | 0.81 | ALDH1A1 (0.57) | TXNRD1TXNRD3TXNRD2ERN1TSHR | |
| SCHEMBL376864 | 0.79 | ALDH1A1 (0.52) | TXNRD1TXNRD3TXNRD2ERN1TSHR | |
| SCHEMBL16309635 | 0.79 | ERN1 (0.61) | TXNRD1TXNRD3TXNRD2ERN1TSHR | |
| SCHEMBL526878 | 0.79 | HSD17B10 (0.60) | TXNRD1TXNRD3TXNRD2ERN1TDP1 | |
| SCHEMBL6172088 | 0.79 | ALDH1A1 (0.60) | TXNRD1TXNRD3TXNRD2ERN1TSHR | |
| SCHEMBL20302595 | 0.79 | GPR35 (0.56) | TXNRD1TXNRD3TXNRD2ERN1TSHR | |
| SCHEMBL38663477 | 0.79 | HSD17B10 (0.60) | TXNRD1TXNRD3TXNRD2ERN1TDP1 | |
| SCHEMBL8464338 | 0.78 | PTPRC (0.52) | TXNRD1TXNRD3TXNRD2ERN1TSHR | |
| SCHEMBL13689920 | 0.77 | HSD17B10 (0.62) | ERN1TSHRLMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860951-A | Modulators of 5-HT receptors and methods of use thereof | AbbVie Deutschland GmbH and Co KG | 2015-08-26 | — | — | CN | disclosed |
| CN-103002735-B | Modulators of 5-ht receptors and methods of use thereof | ABBVI CO | 2015-05-20 | — | — | CN | disclosed |