SCHEMBL28017392

SCHEMBL28017392

Nc1c(C(=O)O)nc(Cl)c(Cl)c1Cl

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.70
LMNA P02545 3/20 0.38
GAA P10253 3/20 0.38
MAPT P10636 3/20 0.38
ATM Q13315 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KMO O15229 1/20 0.36
NOX1 Q9Y5S8 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
GLA P06280 3/20 0.35
HPGD P15428 3/20 0.35
HSD17B10 Q99714 3/20 0.35
PLAU P00749 2/20 0.35
CYP1A2 P05177 2/20 0.35
SLC9A1 P19634 2/20 0.35
SLC22A1 O15245 1/20 0.35
HTR1A P08908 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28016733 0.83 TDP1 (0.70) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL8467014 0.83 TDP1 (1.00) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL29388079 0.83 TDP1 (1.00) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL13299 0.83 TDP1 (1.00) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL7112378 0.81 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL29705200 0.81 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL5086801 0.81 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL28547325 0.81 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Picloram SCHEMBL15437675 0.81 TDP1 (0.96) TDP1LMNAGAAMAPTATM
Ammonia Solution, Strong SCHEMBL28149206 0.81 TDP1 (0.68) TDP1LMNAGAAMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104649965-B The preparation method of 3,4,5,6-4 chloro pyridine formic acid Hunan Bhide biochemical technology company limited (CN) 2016-02-24 CN claimed
CN-104649965-A Preparation method of 3,4,5,6-tetrachloropyridine-2-carboxylic acid HUNAN BIDE BIOTECHNOLOGY CO LTD 2015-05-27 CN claimed
CN-104649965-B The preparation method of 3,4,5,6-4 chloro pyridine formic acid Hunan Bhide biochemical technology company limited (CN) 2016-02-24 CN disclosed
CN-104649965-A Preparation method of 3,4,5,6-tetrachloropyridine-2-carboxylic acid HUNAN BIDE BIOTECHNOLOGY CO LTD 2015-05-27 CN disclosed