⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525806 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL6846159 | 0.76 | — | — | |
| SCHEMBL9755293 | 0.74 | TDP1 (0.35) | — | |
| SCHEMBL19091152 | 0.70 | CA12 (0.34) | — | |
| SCHEMBL8027698 | 0.67 | MME (0.34) | — | |
| SCHEMBL8027704 | 0.67 | MME (0.34) | — | |
| SCHEMBL5838033 | 0.67 | — | — | |
| SCHEMBL20988124 | 0.67 | LMNA (0.40) | — | |
| SCHEMBL1057547 | 0.67 | — | — | |
| SCHEMBL475100 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101835496-B | The multiarm polymers of hydroxyapatite-targeting and the conjugate by its manufacture | NEKTAR THERAPEUTICS (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-103030801-B | Segmented degradable polymers and conjugates made therefrom | NEKTAR THERAPEUTICS AL CORP | 2015-07-22 | — | — | CN | disclosed |