Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027704 | 1.00 | MME (0.34) | MMEACECPA1ACE2TP53 | |
| SCHEMBL23466905 | 0.81 | MME (0.34) | MMEACECPA1ACE2TP53 | |
| SCHEMBL11519870 | 0.79 | MME (0.33) | MMEACECPA1ACE2TP53 | |
| SCHEMBL43589 | 0.72 | SLC6A3 (0.44) | MMEACECPA1ACE2TP53 | |
| SCHEMBL289160 | 0.72 | SLC6A3 (0.44) | MMEACECPA1ACE2TP53 | |
| SCHEMBL43590 | 0.72 | SLC6A3 (0.44) | MMEACECPA1ACE2TP53 | |
| SCHEMBL1716976 | 0.72 | SLC6A3 (0.44) | MMEACECPA1ACE2TP53 | |
| SCHEMBL30255513 | 0.71 | SLC7A5 (0.33) | SLC7A5ALDH1A1 | |
| SCHEMBL525806 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL180064 | 0.70 | TP53 (0.36) | MMEACECPA1ACE2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569132-B1 | Improvements in radiolabelling | ANORMED INC (CA) | 2000-03-01 | — | — | EP | disclosed |
| US-5350837-A | Complexes with 99m Tc suitable for radiolabelling monoclonal antibodies or other macro molecules | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1994-09-27 | — | — | US | disclosed |
| EP-0569132-A1 | Improvements in radiolabelling | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1993-11-10 | — | — | EP | disclosed |