Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019087 | 0.88 | LMNA (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL31628884 | 0.87 | HTT (0.62) | HTTFOLH1LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL8779460 | 0.87 | LMNA (0.54) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL16691249 | 0.87 | LMNA (0.54) | HTTFOLH1LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL4923251 | 0.87 | LMNA (0.54) | HTTFOLH1LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL16691163 | 0.87 | LMNA (0.54) | HTTFOLH1LMNASMN1; SMN2SLC1A3 | |
| SCHEMBL8779454 | 0.87 | LMNA (0.54) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL12667027 | 0.86 | LMNA (0.52) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL19390721 | 0.86 | SMN1; SMN2 (0.52) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL28017164 | 0.85 | HTT (0.48) | HTTLMNASMN1; SMN2SYKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104718190-B | Pyridinone compounds for photodynamic therapy | 埃克塞特大学 | 2017-03-08 | — | — | CN | disclosed |
| CN-104718190-A | Pyridinone compounds for use in photodynamic therapy | UNIV EXETER | 2015-06-17 | — | — | CN | disclosed |