Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.62 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | AHCY | P23526 | 8/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.51 |
| ▸ | GAPDH | P04406 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | PI4KA | P42356 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800776 | 0.90 | PRMT5 (0.64) | PRMT5WDR77AHCYADORA3DPP4 | |
| SCHEMBL800351 | 0.90 | PRMT5 (0.64) | PRMT5WDR77AHCYADORA3DPP4 | |
| SCHEMBL29417875 | 0.86 | EGFR (0.65) | EGFRERBB2PRMT5WDR77AHCY | |
| SCHEMBL101383 | 0.86 | EGFR (0.65) | EGFRERBB2PRMT5WDR77AHCY | |
| SCHEMBL30786566 | 0.83 | EGFR (0.65) | EGFRERBB2AHCYADORA3DPP4 | |
| SCHEMBL2118365 | 0.83 | EGFR (0.65) | EGFRERBB2AHCYADORA3DPP4 | |
| SCHEMBL6894516 | 0.82 | EGFR (0.67) | EGFRERBB2PRMT5WDR77AHCY | |
| SCHEMBL30786567 | 0.81 | EGFR (0.62) | EGFRERBB2AHCYADORA3DPP4 | |
| Putrescine SCHEMBL7124294 | 0.81 | EGFR (0.62) | EGFRERBB2PRMT5WDR77ADORA3 | |
| SCHEMBL397800 | 0.78 | AHCY (0.68) | PRMT5WDR77AHCYADORA3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557358-A | Alkyl trifluoromethyl thioether compound and preparation method thereof | SHANGHAI INSITITUTE OF ORGANIC CHEMISTRY CHINESE ACADEMY OF SCIENCES | 2015-04-29 | — | — | CN | disclosed |