SCHEMBL29417875

SCHEMBL29417875

CC(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](S)[C@@H]1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.65
ERBB2 P04626 1/20 0.65
ADORA3 P0DMS8 4/20 0.55
AHCY P23526 6/20 0.54
ADORA2B P29275 3/20 0.54
KMT2A Q03164 2/20 0.54
ADORA2A P29274 2/20 0.54
ADORA1 P30542 2/20 0.54
HSP90B1 P14625 2/20 0.54
TSHR P16473 1/20 0.54
LMNA P02545 1/20 0.54
THRB P10828 1/20 0.54
BLM P54132 1/20 0.54
HSP90AA1 P07900 1/20 0.54
DOT1L Q8TEK3 2/20 0.54
DPP4 P27487 1/20 0.54
MEN1 O00255 1/20 0.54
SLC28A1 O00337 1/20 0.54
MAP3K7 O43318 1/20 0.54
SLC28A2 O43868 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101383 1.00 EGFR (0.65) EGFRERBB2ADORA3AHCYADORA2B
Putrescine SCHEMBL7124294 0.95 EGFR (0.62) EGFRERBB2ADORA3ADORA2BKMT2A
SCHEMBL22326787 0.90 PRMT5 (0.64) ADORA3AHCYADORA2BKMT2AADORA2A
SCHEMBL13173634 0.90 PRMT5 (0.64) ADORA3AHCYADORA2BKMT2AADORA2A
SCHEMBL800381 0.90 PRMT5 (0.64) ADORA3AHCYADORA2BKMT2AADORA2A
SCHEMBL18520788 0.90 PRMT5 (0.64) ADORA3AHCYADORA2BKMT2AADORA2A
SCHEMBL16300875 0.90 PRMT5 (0.64) ADORA3AHCYADORA2BKMT2AADORA2A
SCHEMBL21413837 0.90 PRMT5 (0.64) ADORA3AHCYADORA2BKMT2AADORA2A
SCHEMBL22326785 0.90 PRMT5 (0.64) ADORA3AHCYADORA2BKMT2AADORA2A
SCHEMBL800346 0.90 PRMT5 (0.64) ADORA3AHCYADORA2BKMT2AADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121577790-A Application of metabolic marker in preparation of eye myasthenia gravis diagnostic reagent 西安市第一医院 2026-02-27 CN claimed
CN-120166925-A Synbiotic composition, metabolite and use thereof for preventing and treating obesity-related diseases 徐丞志 2025-06-17 CN claimed
WO-2025085615-A1 METHODS TO RAPIDLY DETECT METHYLTHIOADENOSINE AND RELATED METABOLITES DIRECTLY FROM PATIENT SAMPLES TO IDENTIFY 9P21 LOSS CANCERS AND TREATMENT STRATEGIES FOR PATIENTS BAYLOR COLLEGE OF MEDICINE (US) 2025-04-24 WO claimed
CN-119752753-A Method for efficiently producing ergothioneine by metabolic engineering escherichia coli and application 江南大学 2025-04-04 CN claimed
CN-116381072-B Biomarker for identifying sporadic gout and frequent gout and application thereof 苏州艾麦锶生命科技有限公司 2024-05-31 CN claimed
CN-118011003-A Biomarker composition for diagnosing gastric cancer and application thereof 哈尔滨脉图精准技术有限公司 2024-05-10 CN claimed
CN-116381072-A Biomarker for identifying sporadic gout and frequent gout and application thereof 青岛大学附属医院 2023-07-04 CN claimed
CN-114515294-A Application of 5' -methylthioadenosine in preparation of obesity inhibition drugs or health care products 浙江中医药大学 2022-05-20 CN claimed
CN-121852489-A Lactobacillus plantarum-derived mixture with antibacterial and anti-inflammatory activities and preparation method and application thereof 广州医科大学附属第一医院(广州呼吸中心) 2026-04-14 CN disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
EP-4705765-A2 BUCCAL CELL DIAGNOSIS OF RISK IN FAMILIAL ARRHYTHMIA SYNDROMES Beth Israel Deaconess Medical Center, Inc. (US) 2026-03-11 EP disclosed
CN-121577790-A Application of metabolic marker in preparation of eye myasthenia gravis diagnostic reagent 西安市第一医院 2026-02-27 CN disclosed
US-20260014125-A1 BICYCLIC-TYPE MAT2A INHIBITOR AND USE THEREOF HAIHE BIOPHARMA CO LTD (CN) 2026-01-15 US disclosed
US-20250282749-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2025-09-11 US disclosed
CN-114515294-A Application of 5' -methylthioadenosine in preparation of obesity inhibition drugs or health care products 浙江中医药大学 2022-05-20 CN disclosed
CN-114515294-A Application of 5' -methylthioadenosine in preparation of obesity inhibition drugs or health care products 浙江中医药大学 2022-05-20 CN disclosed
CN-114515294-A Application of 5' -methylthioadenosine in preparation of obesity inhibition drugs or health care products 浙江中医药大学 2022-05-20 CN disclosed
US-20220127256-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2022-04-28 US disclosed
CN-114107268-A Single-enzyme activity mutant prepared by ACS double-enzyme activity key site mutation of higher plants and application thereof 南开大学 2022-03-01 CN disclosed
CN-114032229-A Single enzyme mutant prepared by replacing ACS double-enzyme activity key structural domain of higher plant and application thereof 南开大学 2022-02-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014125-A1 BICYCLIC-TYPE MAT2A INHIBITOR AND USE THEREOF MAT2A, MNAT1, MAT1A EGFR 4128/4885ERBB2 2751/4885ADORA3 1278/4885
US-20250282749-A1 COMPOUNDS AND METHODS OF USE CYP1B1, CYP2C19, UGT1A1 EGFR 1982/4885ERBB2 3492/4885ADORA3 534/4885
US-20220127256-A1 COMPOUNDS AND METHODS OF USE F12, C1R, ABCG2 EGFR 1299/4885ERBB2 2651/4885ADORA3 55/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 EGFR 383/4885ERBB2 693/4885ADORA3 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.