Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28018515 | 0.82 | KMT2A (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31619459 | 0.81 | PIN1 (0.46) | TSHRPIN1MEN1NPC1KMT2A | |
| SCHEMBL31619467 | 0.81 | PIN1 (0.46) | TSHRPIN1MEN1NPC1KMT2A | |
| SCHEMBL2393254 | 0.81 | PIN1 (0.46) | TSHRPIN1MEN1NPC1KMT2A | |
| SCHEMBL10858287 | 0.81 | TSHR (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31074064 | 0.81 | TSHR (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11766216 | 0.80 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7722451 | 0.79 | TSHR (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27331400 | 0.79 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6354460 | 0.78 | CA12 (0.47) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710305-B | A kind of synthetic method of 2-(2-hydroxy phenyl)-2-fluoroacetic acid ester | 常熟市联创化学有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104710305-A | Synthetic method for 2-(2-hydroxyphenyl)-2-oxyacetate | CHANGSHU LEAGUE CHEMICAL CO LTD | 2015-06-17 | — | — | CN | disclosed |