Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858287 | 1.00 | TSHR (0.53) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL11410848 | 0.89 | NLRP3 (0.53) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL490582 | 0.86 | CA1 (0.51) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL363983 | 0.85 | TSHR (0.48) | TSHRSMN1; SMN2LMNAPIN1KMT2A | |
| SCHEMBL28008252 | 0.84 | NLRP3 (0.50) | TSHRSMN1; SMN2LMNAPIN1KMT2A | |
| SCHEMBL11683620 | 0.83 | CA12 (0.49) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL6718334 | 0.83 | CA12 (0.49) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL10825007 | 0.83 | TSHR (0.50) | TSHRGABRA1GABRB2SMN1; SMN2LMNA | |
| SCHEMBL11409544 | 0.83 | TSHR (0.44) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL5379799 | 0.82 | CA1 (0.47) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024183807-A1 | ARYL FUSED IMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 哈尔滨三联药业股份有限公司 | 2024-09-12 | — | — | WO | disclosed |