Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688754 | 0.83 | GAA (0.54) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL688269 | 0.83 | GAA (0.54) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL4641369 | 0.82 | GAA (0.52) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL27642915 | 0.80 | ALDH1A1 (0.55) | GAAMAPTLMNAKMT2AHPGD | |
| SCHEMBL689958 | 0.80 | KMT2A (0.51) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL4644681 | 0.80 | GAA (0.50) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL1085665 | 0.80 | GAA (0.50) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL361508 | 0.80 | GAA (0.50) | GAAJAK2MAPTLMNAKMT2A | |
| SCHEMBL4645662 | 0.80 | GAA (0.50) | GAAJAK2MAPTLMNAKMT2A | |
| Methane SCHEMBL10713153 | 0.78 | GAA (0.48) | GAAJAK2MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710305-B | A kind of synthetic method of 2-(2-hydroxy phenyl)-2-fluoroacetic acid ester | 常熟市联创化学有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104710305-A | Synthetic method for 2-(2-hydroxyphenyl)-2-oxyacetate | CHANGSHU LEAGUE CHEMICAL CO LTD | 2015-06-17 | — | — | CN | disclosed |