Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777175 | 0.77 | USP2 (0.39) | ALDH1A1LMNATSHR | |
| SCHEMBL779758 | 0.77 | USP2 (0.39) | ALDH1A1LMNATSHR | |
| SCHEMBL2720592 | 0.75 | ALDH1A1 (0.37) | ALDH1A1LMNATSHR | |
| SCHEMBL23082615 | 0.74 | MGAM (0.31) | PAOXGAAMGAMSIMGAM2 | |
| SCHEMBL18265863 | 0.73 | — | — | |
| SCHEMBL16656477 | 0.73 | ALDH1A1 (0.45) | ALDH1A1PAOXACHELMNAGAA | |
| SCHEMBL12927394 | 0.73 | APP (0.46) | ALDH1A1PAOXACHELMNAGAA | |
| SCHEMBL14052909 | 0.72 | ACHE (0.35) | ALDH1A1PAOXACHELMNAGAA | |
| SCHEMBL20306149 | 0.72 | CYP2C19 (0.38) | POLB | |
| SCHEMBL7019733 | 0.72 | KDM4E (0.52) | ALDH1A1PAOXTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662004-A | Novel rebamipide prodrug, method for producing same, and usage thereof | SAMJIN PHARM CO LTD | 2015-05-27 | — | — | CN | disclosed |