SCHEMBL28018199

SCHEMBL28018199

c1ccc2c(SOSc3occ4ccccc34)occ2c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP2A6 P11509 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GPR3 P46089 1/20 0.33
CYP3A4 P08684 1/20 0.31
HPRT1 P00492 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20004029 0.77 TDP1 (0.37) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL13183713 0.72 ELANE (0.39) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL6001561 0.67 ALDH1A1 (0.38) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL547450 0.64 PTPN1 (0.39) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL4079696 0.64 CYP2A6 (0.42) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL2008998 0.64 ALDH1A1 (0.42) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL286416 0.64 ALDH1A1 (0.39) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL1097671 0.64 CYP2A6 (0.42) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL1605255 0.64 ALDH1A1 (0.39) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL21179481 0.64 ALDH1A1 (0.39) ALDH1A1CYP2A6TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104725172-B A kind of synthetic method of aryl thioethers class compound 华东师范大学 2017-03-01 CN disclosed
CN-104725172-A Synthetic method of aryl sulfide type compound UNIV EAST CHINA NORMAL 2015-06-24 CN disclosed