SCHEMBL28018200

SCHEMBL28018200

C=CC(=O)OC(C)CCP(=O)(O)O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.40
ALDH1A1 P00352 6/20 0.36
TDP1 Q9NUW8 1/20 0.36
FOLH1 Q04609 1/20 0.33
ENPEP Q07075 1/20 0.32
S1PR2 O95136 5/20 0.32
S1PR1 P21453 5/20 0.32
S1PR3 Q99500 5/20 0.32
S1PR4 O95977 4/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27531933 0.90 ALDH1A1 (0.46) TSHRALDH1A1TDP1ENPEPCYP3A4
SCHEMBL672062 0.82 TSHR (0.50) TSHRALDH1A1TDP1TP53HIF1A
SCHEMBL28051429 0.82 TSHR (0.36) TSHRALDH1A1TDP1TP53HIF1A
SCHEMBL977700 0.81 TSHR (0.42) TSHRALDH1A1FOLH1TP53HIF1A
Phosphoric Acid SCHEMBL6672840 0.81 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28405006 0.80 TSHR (0.36) TSHRALDH1A1TDP1CYP3A4HPGD
Phosphoric Acid SCHEMBL28245033 0.79 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27994980 0.79 LPAR3 (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5173034 0.79 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
Phosphoric Acid SCHEMBL28853862 0.78 TSHR (0.37) TSHRALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111867848-B Lithographic printing plate precursor and method for producing lithographic printing plate precursor 富士胶片株式会社 2021-10-15 CN disclosed
CN-111867848-A Lithographic printing plate precursor and method for producing lithographic printing plate precursor 富士胶片株式会社 2020-10-30 CN disclosed
CN-107206828-B Original edition of lithographic printing plate, its manufacturing method and the printing process using it 富士胶片株式会社 2019-10-25 CN disclosed
CN-107206828-A Original edition of lithographic printing plate, its manufacture method and utilize its printing process 富士胶片株式会社 2017-09-26 CN disclosed
CN-104736580-A Polyvinyl acetal microparticles for water-based dispersion SEKISUI CHEMICAL CO LTD 2015-06-24 CN disclosed