Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27418121 | 0.91 | TSHR (0.42) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Phosphoric Acid SCHEMBL28245033 | 0.81 | TSHR (0.38) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL672062 | 0.81 | TSHR (0.50) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL28018200 | 0.81 | TSHR (0.40) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Phosphoric Acid SCHEMBL28190646 | 0.80 | TSHR (0.42) | TSHRALDH1A1TP53CYP3A4HIF1A | |
| Phosphoric Acid SCHEMBL28189975 | 0.80 | TSHR (0.37) | TSHRALDH1A1CYP3A4HPGD | |
| Phosphoric Acid SCHEMBL28189998 | 0.80 | TSHR (0.41) | TSHRALDH1A1CYP3A4HPGD | |
| Phosphoric Acid SCHEMBL28853862 | 0.80 | TSHR (0.37) | TSHRALDH1A1CYP3A4HPGD | |
| Phosphoric Acid SCHEMBL28245025 | 0.79 | TSHR (0.36) | TSHRALDH1A1TP53CYP3A4HIF1A | |
| Phosphoric Acid SCHEMBL28245024 | 0.79 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGDFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462079-A1 | Dental composition | GC Corporation (JP) | 2004-09-29 | — | — | EP | disclosed |