Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39239 | 0.89 | KDM4E (0.58) | LPLLIPGKDM4EALDH1A1CA2 | |
| SCHEMBL29155090 | 0.87 | KDM4E (0.56) | LPLLIPGKDM4EALDH1A1CA2 | |
| SCHEMBL28691270 | 0.87 | KDM4E (0.56) | LPLLIPGKDM4EALDH1A1CA2 | |
| Lithium SCHEMBL31590907 | 0.87 | KDM4E (0.56) | LPLLIPGKDM4EALDH1A1CA2 | |
| Alcohol SCHEMBL28211838 | 0.84 | ALDH1A1 (0.65) | ALDH1A1CA2CA1TSHR | |
| SCHEMBL13621940 | 0.83 | CA2 (0.54) | LPLLIPGKDM4EALDH1A1CA2 | |
| Styrene SCHEMBL28036433 | 0.81 | ALDH1A1 (0.61) | LPLLIPGKDM4EALDH1A1CA2 | |
| Acetic Acid SCHEMBL28317701 | 0.80 | KDM4E (0.50) | LPLLIPGKDM4EALDH1A1CA2 | |
| Alcohol SCHEMBL28611219 | 0.79 | KDM4E (0.79) | LPLLIPGKDM4EALDH1A1CA2 | |
| Acrylamide SCHEMBL28211334 | 0.76 | KDM4E (0.50) | LPLLIPGKDM4EALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304732-B | Monodisperse core-shell structure polymer nano particle as well as preparation and application thereof | DALIAN CHEMICAL PHYSICS INST | 2015-07-01 | — | — | CN | claimed |