Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580693 | 0.86 | EGFR (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL23674627 | 0.86 | LMNA (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL30100786 | 0.86 | LMNA (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL28018204 | 0.86 | MEN1 (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL4857531 | 0.80 | DYRK1A (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL29801631 | 0.80 | DYRK1A (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20787974 | 0.80 | KCNH2 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20604669 | 0.80 | MEN1 (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL5622616 | 0.79 | SMN1; SMN2 (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL15815917 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104649854-A | Cheap and efficient preparation method of aryl halides | UNIV BEIJING | 2015-05-27 | — | — | CN | disclosed |