Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.73 |
| ▸ | FAAH | O00519 | 4/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119423 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 | |
| SCHEMBL220549 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 | |
| SCHEMBL165446 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 | |
| SCHEMBL17453344 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 | |
| SCHEMBL1333273 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 | |
| SCHEMBL221500 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 | |
| SCHEMBL8345479 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 | |
| SCHEMBL21345153 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 | |
| SCHEMBL21240011 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 | |
| SCHEMBL10937974 | 0.98 | DNM1 (0.71) | DNM1FAAHTRPV1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111718716-A | Nanostructures with inorganic ligands for electroluminescent devices | 纳米系统公司 | 2020-09-29 | — | — | CN | disclosed |
| CN-104837479-B | Vesicle composition, and external preparation for skin and cosmetic containing the same | 株式会社高丝 | 2018-01-09 | — | — | CN | disclosed |
| CN-104837479-A | Vesicle composition, and external preparation for skin and cosmetic containing the same | KOSE CORP | 2015-08-12 | — | — | CN | disclosed |