SCHEMBL1333273

SCHEMBL1333273

CCCCCC/C=C\CCCCCCCCN(C)C

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.71
FAAH O00519 4/20 0.54
TRPV1 Q8NER1 1/20 0.54
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
EPHX2 P34913 4/20 0.51
TERT O14746 3/20 0.47
CYP1A2 P05177 2/20 0.47
MAPT P10636 2/20 0.47
CYP2C19 P33261 2/20 0.47
BLM P54132 2/20 0.47
HSD17B10 Q99714 2/20 0.47
FABP4 P15090 2/20 0.47
PTPN1 P18031 2/20 0.47
PPARG P37231 2/20 0.47
KMT2A Q03164 2/20 0.47
PPARD Q03181 2/20 0.47
PPARA Q07869 2/20 0.47
GMNN O75496 1/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119423 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR
SCHEMBL10937974 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR
SCHEMBL17453344 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR
SCHEMBL220549 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR
SCHEMBL21240011 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR
SCHEMBL8345479 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR
SCHEMBL221500 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR
SCHEMBL165446 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR
SCHEMBL21345153 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR
SCHEMBL8004895 1.00 DNM1 (0.71) DNM1FAAHTRPV1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2566874-B1 SOLVENT-FREE ORGANOSILANE QUATERNARY AMMONIUM COMPOSITIONS, METHOD OF MAKING AND USE RESOURCE DEV LLC (US) 2023-01-18 EP claimed
US-8735618-B2 Solvent-free organosilane quaternary ammonium compositions, method of making and use RESOURCE DEVELOPMENT L.L.C. (US) 2014-05-27 US claimed
EP-2566874-A2 SOLVENT-FREE ORGANOSILANE QUATERNARY AMMONIUM COMPOSITIONS, METHOD OF MAKING AND USE Resource Development L.L.C. (US) 2013-03-13 EP claimed
US-20120125226-A1 Solvent-Free Organosilane Quaternary Ammonium Compositions, Method of Making and Use RESOURCE DEVELOPMENT L.L.C. (US) 2012-05-24 US claimed
WO-2011140451-A2 SOLVENT-FREE ORGANOSILANE QUATERNARY AMMONIUM COMPOSITIONS, METHOD OF MAKING AND USE RESOURCE DEVELOPMENT L.L.C. (US) 2011-11-10 WO claimed
US-20110271873-A1 Solvent-Free Organosilane Quaternary Ammonium Compositions, Method of Making and Use Resource Development, LLC (US) 2011-11-10 US claimed
EP-0839529-A2 Compositions containing aliphatic monocarboxylic acid esters or amides for the treatment of skin diseases CELLEGY PHARMACEUTICALS, INC. (US) 1998-05-06 EP claimed
JP-2513877-B2 1996-07-03 JP claimed
US-5231087-A Treatment of skin diseases and tumors with esters and amides of monocarboxylic acids CELLEGY PHARMACEUTICALS, INC. (US) 1993-07-27 US claimed
EP-0515517-A4 TREATMENT OF PRURITIS WITH ESTERS AND AMIDES 1993-05-19 EP claimed
EP-0462964-A4 TREATMENT OF SKIN DISEASES AND TUMORS 1993-02-10 EP claimed
EP-0515517-A1 TREATMENT OF PRURITIS WITH ESTERS AND AMIDES DERMATOLOGIC RESEARCH CORPORATION (US) 1992-12-02 EP claimed
EP-0462964-A1 TREATMENT OF SKIN DISEASES AND TUMORS CELLEGY PHARMACEUTICALS, INC. (US) 1992-01-02 EP claimed
US-5057500-A TREATMENT OF PRURITIS WITH ESTERS AND AMIDES DERMATOLOGIC RESEARCH CORPORATION (US) 1991-10-15 US claimed
WO-1991012010-A1 TREATMENT OF PRURITIS WITH ESTERS AND AMIDES DERMATOLOGIC RESEARCH CORPORATION (US) 1991-08-22 WO claimed
WO-1990010441-A1 TREATMENT OF SKIN DISEASES AND TUMORS THORNFELDT CARL R (US) 1990-09-20 WO claimed
EP-2566874-B1 SOLVENT-FREE ORGANOSILANE QUATERNARY AMMONIUM COMPOSITIONS, METHOD OF MAKING AND USE RESOURCE DEV LLC (US) 2023-01-18 EP disclosed
US-8735618-B2 Solvent-free organosilane quaternary ammonium compositions, method of making and use RESOURCE DEVELOPMENT L.L.C. (US) 2014-05-27 US disclosed
US-5057500-A TREATMENT OF PRURITIS WITH ESTERS AND AMIDES DERMATOLOGIC RESEARCH CORPORATION (US) 1991-10-15 US disclosed
WO-1990010441-A1 TREATMENT OF SKIN DISEASES AND TUMORS THORNFELDT CARL R (US) 1990-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120125226-A1 Solvent-Free Organosilane Quaternary Ammonium Compositions, Method of Making and Use VDAC1, CUTA, HVCN1 DNM1 876/4885FAAH 1272/4885TRPV1 1253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.