Pyridine

Pyridine

SCHEMBL28019201

O=C(c1ccccn1)c1ccccn1.c1ccncc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.70
LMNA P02545 2/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
NAPRT Q6XQN6 1/20 0.65
P4HTM Q9NXG6 1/20 0.65
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 1/20 0.57
GSK3B P49841 1/20 0.52
RAB9A P51151 4/20 0.50
NPC1 O15118 3/20 0.50
MAPT P10636 1/20 0.50
PKM P14618 1/20 0.50
HSD17B14 Q9BPX1 1/20 0.49
MEN1 O00255 2/20 0.48
PTGS2 P35354 1/20 0.47
HTT P42858 1/20 0.46
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31369148 0.91 KMT2A (0.75) KMT2ALMNAL3MBTL1NAPRTP4HTM
SCHEMBL87791 0.91 KMT2A (0.75) KMT2ALMNAL3MBTL1NAPRTP4HTM
Hydrochloric Acid SCHEMBL27723543 0.89 KMT2A (0.72) KMT2ALMNAL3MBTL1NAPRTP4HTM
Water SCHEMBL6228901 0.89 KMT2A (0.72) KMT2ALMNAL3MBTL1NAPRTP4HTM
Charcoal, Activated SCHEMBL8358164 0.89 KMT2A (0.72) KMT2ALMNAL3MBTL1NAPRTP4HTM
SCHEMBL31369119 0.89 KMT2A (0.72) KMT2ALMNAL3MBTL1NAPRTP4HTM
Acetic Acid SCHEMBL28040553 0.87 KMT2A (0.70) KMT2ALMNAL3MBTL1NAPRTP4HTM
2-Picolinic Acid SCHEMBL28365061 0.87 LMNA (0.87) KMT2ALMNAL3MBTL1NAPRTP4HTM
2-Picolinic Acid SCHEMBL4813302 0.87 LMNA (0.87) KMT2ALMNAL3MBTL1NAPRTP4HTM
Phenol SCHEMBL17644331 0.85 KMT2A (0.68) KMT2ALMNAL3MBTL1NAPRTP4HTM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104739759-B A kind of pharmaceutical composition containing milrinone compound 海南合瑞制药股份有限公司 2018-03-02 CN disclosed
CN-104739759-A Pharmaceutical composition containing milrinone compound HAINAN HERUI PHARMACEUTICAL CO LTD 2015-07-01 CN disclosed