Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.87 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.87 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.87 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.87 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Picolinic Acid SCHEMBL28365061 | 1.00 | LMNA (0.87) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL27883128 | 0.98 | LMNA (0.83) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL29368665 | 0.93 | — | — | |
| 2-Picolinic Acid SCHEMBL674837 | 0.93 | LMNA (1.00) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL7457912 | 0.93 | LMNA (1.00) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL28737810 | 0.93 | LMNA (1.00) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL36055 | 0.93 | — | — | |
| 2-Picolinic Acid SCHEMBL6260363 | 0.92 | LMNA (0.80) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL3843691 | 0.91 | LMNA (0.95) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL3732328 | 0.91 | LMNA (0.95) | LMNAL3MBTL1NAPRTP4HTMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658912-A | Methyl lotus alkaloid derivative intermediate and preparation method and application thereof | 中南大学湘雅医院 | 2024-03-08 | — | — | CN | claimed |
| US-5830867-A | Hemoregulatory peptides for stimulating the myelopoietic system | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-03 | — | — | US | claimed |
| US-5545761-A | USING OXIDATION CATALYSTS | ARISTECH CHEMICAL CORPORATION (US) | 1996-08-13 | — | — | US | claimed |
| CN-117658912-A | Methyl lotus alkaloid derivative intermediate and preparation method and application thereof | 中南大学湘雅医院 | 2024-03-08 | — | — | CN | disclosed |
| CN-115867586-A | Electrochemically debondable adhesive compositions | 汉高股份有限及两合公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-110563662-A | Compound and organic electronic device thereof | 上海嵘彩光电材料有限公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-109403069-A | A kind of dyeing of TR looped fabric | 绍兴华星丝织印染有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-108299465-A | A kind of drug and preparation method thereof for treating pancreatitis | 牡丹江医学院 | 2018-07-20 | — | — | CN | disclosed |
| CN-104988531-B | The method that a kind of selective dechlorination of chloro-pyridine formic acid electro-catalysis prepares pyridine carboxylic acid | 浙江工业大学 | 2017-11-07 | — | — | CN | disclosed |
| CN-104988531-A | Method for preparing picolinic acid through electro-catalysis selective dechloridation of chloropicolinicacid | UNIV ZHEJIANG TECHNOLOGY | 2015-10-21 | — | — | CN | disclosed |
| US-7390904-B2 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-06-24 | — | — | US | disclosed |
| EP-1644329-A1 | HYDROGEN PEROXIDE CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-HYDROCARBYLOXYAMINES | Ciba SC Holding AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| US-20050014948-A1 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-20 | — | — | US | disclosed |
| WO-2005005388-A1 | HYDROGEN PEROXIDE CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-HYDROCARBYLOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014948-A1 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | HAO2, SOD1, PPOX | LMNA 3323/4885L3MBTL1 2577/4885NAPRT 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.