SCHEMBL28019342

SCHEMBL28019342

[CH2]C[C@H](CCCCCCCCCCC)OCCCCCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.53
LPAR1 Q92633 6/20 0.41
LPAR3 Q9UBY5 6/20 0.41
LPAR2 Q9HBW0 3/20 0.41
ALDH1A1 P00352 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
LPAR6 P43657 2/20 0.38
LPAR4 Q99677 2/20 0.38
LPAR5 Q9H1C0 2/20 0.38
TLR2 O60603 6/20 0.38
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4495268 0.98 DNM1 (0.50) DNM1LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL27900394 0.96 DNM1 (0.48) DNM1LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL4488921 0.94 DNM1 (0.45) DNM1LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL4498566 0.94 DNM1 (0.50) DNM1LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL6050344 0.92 DNM1 (0.53) DNM1LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL11203185 0.90 DNM1 (0.48) DNM1LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL9470762 0.90 DNM1 (0.48) DNM1LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL9469822 0.90 DNM1 (0.48) DNM1LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL11203189 0.90 DNM1 (0.48) DNM1LPAR1LPAR3LPAR2ALDH1A1
SCHEMBL29221553 0.90 DNM1 (0.48) DNM1LPAR1LPAR3LPAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105001276-B A kind of less toxic Kdo2The preparation and its application of MPLA 江南大学 2018-03-16 CN claimed
CN-104844665-B A kind of Kdo of the low toxicity containing five fatty acid chains2The preparation and application of MPLA 江南大学 2018-03-16 CN claimed
CN-105001276-A Novel low-toxicity Kdo2Preparation of monophosphoryl lipid A and application thereof UNIV JIANGNAN 2015-10-28 CN claimed
CN-104844665-A Preparation and application of low-toxicity Kdo2-monophosphoryl lipid A containing five fatty acid chains UNIV JIANGNAN 2015-08-19 CN claimed
CN-105001276-B A kind of less toxic Kdo2The preparation and its application of MPLA 江南大学 2018-03-16 CN disclosed
CN-104844665-B A kind of Kdo of the low toxicity containing five fatty acid chains2The preparation and application of MPLA 江南大学 2018-03-16 CN disclosed
CN-105001276-A Novel low-toxicity Kdo2Preparation of monophosphoryl lipid A and application thereof UNIV JIANGNAN 2015-10-28 CN disclosed
CN-104844665-A Preparation and application of low-toxicity Kdo2-monophosphoryl lipid A containing five fatty acid chains UNIV JIANGNAN 2015-08-19 CN disclosed