SCHEMBL6050344

SCHEMBL6050344

[CH2]CC(CCC)OCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.53
LPAR1 Q92633 6/20 0.41
LPAR3 Q9UBY5 6/20 0.41
LPAR2 Q9HBW0 3/20 0.41
CNR1 P21554 3/20 0.40
CNR2 P34972 3/20 0.40
ALDH1A1 P00352 1/20 0.40
LPAR6 P43657 2/20 0.38
LPAR4 Q99677 2/20 0.38
LPAR5 Q9H1C0 2/20 0.38
TLR2 O60603 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4482395 0.98 DNM1 (0.50) DNM1LPAR1LPAR3LPAR2CNR1
SCHEMBL28019342 0.92 DNM1 (0.53) DNM1LPAR1LPAR3LPAR2CNR1
SCHEMBL4490936 0.91 DNM1 (0.42) DNM1LPAR1LPAR3LPAR2CNR1
SCHEMBL4495268 0.89 DNM1 (0.50) DNM1LPAR1LPAR3LPAR2CNR1
SCHEMBL4498566 0.89 DNM1 (0.50) DNM1LPAR1LPAR3LPAR2CNR1
SCHEMBL27900394 0.88 DNM1 (0.48) DNM1LPAR1LPAR3LPAR2CNR1
SCHEMBL22654529 0.87 DNM1 (0.61) DNM1LPAR1LPAR3LPAR2CNR1
SCHEMBL22654528 0.87 DNM1 (0.61) DNM1LPAR1LPAR3LPAR2CNR1
SCHEMBL9469822 0.86 DNM1 (0.48) DNM1LPAR1LPAR3LPAR2CNR1
SCHEMBL29221553 0.86 DNM1 (0.48) DNM1LPAR1LPAR3LPAR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180108947-A9 ELECTROLYTE AND LITHIUM-ION BATTERY CONTAINING THE SAME NINGDE AMPEREX TECHNOLOGY LTD. (CN) 2018-04-19 US disclosed
US-20170084956-A1 ELECTROLYTE AND LITHIUM-ION BATTERY CONTAINING THE SAME Amperex Technology Limited (CN) 2017-03-23 US disclosed
EP-1084710-B1 ADENOSINE A1 ANTAGONISTS FOR MALE STERILITY ASTELLAS PHARMA INC (JP) 2006-10-18 EP disclosed
US-20040152659-A1 Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2004-08-05 US disclosed
US-6521656-B1 Contacting sperm with a pyrazolo(1,5-a)pyridine acrosomal reaction induction promoter then joining with ovum FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-02-18 US disclosed
EP-0925299-B1 PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF FUJISAWA PHARMACEUTICAL CO (JP) 2002-09-25 EP disclosed
EP-0823254-B1 NOVEL USE OF PYRAZOLOPYRIDINE COMPOUNDS FUJISAWA PHARMACEUTICAL CO (JP) 2002-07-17 EP disclosed
EP-1177797-A9 NOVEL USE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-05-15 EP disclosed
US-6355640-B1 TREATMENT OF HYPERTENSION, UROGENITAL DISORDERS AND FORMED BY WITTIG REACTION FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-03-12 US disclosed
EP-1177797-A1 NOVEL USE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-02-06 EP disclosed
EP-0497258-A2 Use of adenosine antagonists in the prevention and treatment of pancreatitis and ulcer FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-08-05 EP disclosed
US-5102878-A Treating psychological, bone, cardiovascular, blood disorders FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-04-07 US disclosed
US-5102869-A Urogenital disorders FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-04-07 US disclosed
US-5087629-A Diuretics, hypotensive agents; cardiotonic agents FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-02-11 US disclosed
US-4994453-A Treating asthma, diabetes, obesity, immunosuppression FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-02-19 US disclosed
US-4985444-A Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-01-15 US disclosed
CN-1044656-A Pyrazolopyridine compound and preparation method thereof FUJISAWA PHARMACEUTICAL CO (JP) 1990-08-15 CN disclosed
US-4925849-A DIURETICS, HYPOTENSIVE AGENTS, CARIOTONIC AGENTS AND ANTIEDEMIC AGENTS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-15 US disclosed
CN-1031376-A Pyrazolopyridine compound and preparation method thereof FUJISAWA PHARMACEUTICAL CO (JP) 1989-03-01 CN disclosed
EP-0299209-A2 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152659-A1 Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist ADORA2A, ADORA1, ADORA2B DNM1 1124/4885LPAR1 106/4885LPAR3 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.