Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292221 | 0.88 | SSTR4 (0.39) | SSTR4HTR2ASLC6A4ADRB2HTR1A | |
| SCHEMBL1655323 | 0.82 | ADRA2C (0.42) | SSTR4HTR2ASLC6A4ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL15550523 | 0.81 | ADRA2C (0.41) | SSTR4HTR2ASLC6A4ADRB2HTR1A | |
| SCHEMBL29121107 | 0.80 | EPHX2 (0.38) | SSTR4HTR2ASLC6A4ADRB2HTR1A | |
| SCHEMBL2921129 | 0.79 | SLC6A2 (0.43) | SSTR4HTR2ASLC6A4ADRB2HTR1A | |
| SCHEMBL27609653 | 0.79 | SLC6A2 (0.38) | SSTR4HTR2ASLC6A4ADRB2HTR1A | |
| SCHEMBL30275082 | 0.79 | SLC6A2 (0.43) | SSTR4HTR2ASLC6A4ADRB2HTR1A | |
| SCHEMBL754567 | 0.78 | HCRTR2 (0.40) | SSTR4HTR2ASLC6A4ADRB2HTR1A | |
| SCHEMBL12070332 | 0.78 | HCRTR2 (0.40) | SSTR4HTR2ASLC6A4ADRB2HTR1A | |
| SCHEMBL1266666 | 0.78 | HCRTR2 (0.40) | SSTR4HTR2ASLC6A4ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244047-A | Indazole derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-110573508-B | Fused imidazo-piperidine JAK inhibitor compounds | 施万生物制药研发IP有限责任公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-110573508-A | Fused imidazo-piperidine JAK inhibitor compounds | 施万生物制药研发IP有限责任公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-106008466-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2018-12-14 | — | — | CN | disclosed |
| CN-105873920-B | As 5-HT4The indazole compound of receptor stimulating agent | 苏文生命科学有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-106008466-A | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | 艾伯维公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105873920-A | Indazole compounds as 5-HT4 receptor agonists | 苏文生命科学有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-102307622-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104906100-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBOTT LAB | 2015-09-16 | — | — | CN | disclosed |
| CN-104876927-A | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LAB | 2015-09-02 | — | — | CN | disclosed |
| CN-104812740-A | Novel acetamide derivatives as TRP channel antagonists | HOFFMANN LA ROCHE | 2015-07-29 | — | — | CN | disclosed |
| CN-102448959-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE BAHAMAS LTD | 2015-06-17 | — | — | CN | disclosed |