Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 9/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | FECH | P22830 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019673 | 0.88 | SSTR4 (0.39) | SSTR4SLC6A2SLC6A4ADRB2HTR1A | |
| SCHEMBL1655323 | 0.77 | ADRA2C (0.42) | SSTR4SLC6A2SLC6A4ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL15550523 | 0.76 | ADRA2C (0.41) | SSTR4SLC6A2SLC6A4ADRB2HTR1A | |
| SCHEMBL1266666 | 0.76 | HCRTR2 (0.40) | SSTR4SLC6A2SLC6A4ADRB2HTR1A | |
| SCHEMBL12070332 | 0.76 | HCRTR2 (0.40) | SSTR4SLC6A2SLC6A4ADRB2HTR1A | |
| SCHEMBL754567 | 0.76 | HCRTR2 (0.40) | SSTR4SLC6A2SLC6A4ADRB2HTR1A | |
| SCHEMBL29121107 | 0.76 | EPHX2 (0.38) | SSTR4SLC6A2SLC6A4ADRB2HTR1A | |
| SCHEMBL22301022 | 0.74 | MEN1 (0.41) | SSTR4SLC6A2SLC6A4 | |
| SCHEMBL17293005 | 0.73 | — | — | |
| SCHEMBL21069547 | 0.72 | SLC6A4 (0.34) | SSTR4SLC6A2SLC6A4ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170489-B | New Pyrazolopyrimidine derivative and its purposes as MALT1 inhibitor | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |